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Medizinische FakultätZentrum Anatomie

Publikationen

2017

  • Cozzi, B., Mazzariol, S.,Podestà, M., Zotti, A.,Huggenberger, S. 2017: An unparalleled sexual dimorphism of sperm whale encephalization. International Journal of Comparative Psychology.
  • Huggenberger, S., Leidenberger, S., Oelschläger, H.H.A. 2017: Asymmetry of nasofacial skulls of toothed whales (Odontoceti). Journal of Zoology.
  • Klingebiel M, Dinekov M, Köhler C.: Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus.Brain Research 1659, 15 March 2017, Pages 121–135. doi: 10.1016/j.brainres.2017.01.016

2016

  • Köhler C.: Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology. Acta Neuropathol. 2016 Sep;132(3):339-59. doi: 10.1007/s00401-016-1562-0. Review.
  • Cozzi, B., Huggenberger, S., Oelschläger, H.H.A. 2016: The Anatomy of Dolphins - Insights into Body Structure and Function. San Diego: Academic Press. 438pp. ISBN: 978-0-12-407229-9.
  • Steinhausen, C., Zehl, L., Haas-Rioth, M., Morcinek K., Walkowiak, W., Huggenberger, S. 2016: Multivariate meta-analysis of brain-mass correlations in eutherian mammals. Frontiers in Neuroanatomy, doi: 10.3389/fnana.2016.00091. (Abstract)
  • Huggenberger, S., André, M., Oelschläger, H.H.A. 2016: The nose of the sperm whale: overviews of functional design, structural homologies and evolution. Journal of the Marine Biological Association of the United Kingdom 96: 783-806.

2015

  • Huggenberger, S., Oelschläger, H.H.A. 2015: Moby Dicks Boombox. Spektrum der Wissenschaft 9: 10-12.
  • Huggenberger, S. 2015: Anatomie – Stirbt die vergleichende Kunst aus? Naturwissenschaftliche Rundschau 6: 294-300.
  • Huggenberger, S., Klima, M. 2015: Cetacea, Waltiere. In: Spezielle Zoologie. Bd.2, Wirbeltiere. 3. neubearbeitete Auflage. (Eds. Westheide, W., Rieger, G.) Heidelberg: Spektrum Akademischer Verlag. Pp. 600-613.
  • Frainer, G., Huggenberger, S., Moreno, I.B. 2015: Postnatal allometric changes in the nasal apparatus of the franciscana (Pontoporia blainvillei) - functional implications. Marine Mammal Science 31: 1193-1212.
  • Cozzi, B., Podestà, M., Vaccaro, C., Poggi, R., Mazzariol, S., Huggenberger, S., Zotti, A. 2015: Precocious ossification of the tympanic bulla in fetal and newborn dolphins: an evolutionary adaptation to the aquatic environment? Anatomical Record 298: 1294-1300.

2014

  • Huggenberger, S., André, M., Oelschläger, H.H.A. 2014: An acoustic valve within the nose of sperm whales. Mammal Review 44: 81-87.
  • Köhler C, Dinekov M, Götz J.: Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis. Neurobiol Dis. 2014 Nov;71:169-79. doi: 10.1016/j.nbd.2014.07.006. Epub 2014 Jul 27. (Abstract)
  • Neuhaus JF, Baris OR, Hess S, Moser N, Schröder H, Chinta SJ, Andersen JK, Kloppenburg P, Wiesner RJ.: Catecholamine metabolism drives generation of mitochondrial DNA deletions in dopaminergic neurons. Brain. 2014 Feb;137(Pt 2):354-65. doi: 10.1093/brain/awt291. Epub 2013 Oct 24. [Epub ahead of print] (Abstract)

2013

 

  • Köhler C, Dinekov M, Götz J: Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice. Neurobiol Aging. 2013 May;34(5):1369-79. [doi: 10.1016/j.neurobiolaging.2012.11.010.] Epub 2013 Jan 4. (Abstract)
  • Morcinek K, Köhler C, Götz J, Schröder H: Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice. Brain Res. 2013 Feb 25;1497:73-84. [doi: 10.1016/j.brainres.2012.12.0160.] Epub 2012 Dec 20. (Abstract)

2012

  • Ke Y, Dramiga J, Schütz U, Kril J, Ittner LM, Schröder H, Götz J: Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease. PLoS ONE 7(4):e35678 (2012) [doi:10.1371/journal.pone.0035678] (Abstract)

2011

 

  • Köhler C. Histochemical localization of caldesmon isoforms in colon adenocarcinoma and lymph node metastases. Virchows Arch. 2011 May 29. [Epub ahead of print] DOI: 10.1007/s00428-011-1091-0 (Abstract)
  • Köhler C. Histochemical localization of caldesmon in the CNS and Ganglia of the mouse. J Histochem Cytochem (2011) 59:504-17 (2011) (Abstract)
  • Wevers A: Localisation of pre- and postsynaptic cholinergic markers in the human brain. Behav Brain Res. 2011 Aug 10;221(2):341-55. [doi: 10.1016/j.bbr.2010.02.025] Epub 2010 Feb 16. (Abstract)

2010

 

  • Kiryakova, S., Söhnchen J, Grosheva M, Schütz U, Mariniova TS, Dzhupanova R, Sinis N, Hubbers CU, Skouras E, Ankerne J, Fries JW, Irintchev A, Dunlop SA, Angelov DN: Recovery of whisking function promoted by manual stimulation of the vibrissal muscles after facial nerve injury requires insulin-like growth factor 1 (IGF-1). Exp Neurol 222:226-234 (2010) (Abstract)
  • Köhler C: The Actin-binding Protein Caldesmon Is in Spleen and Lymph Nodes Predominately Expressed by Smooth Muscle Cells, Reticular Cells, and Follicular Dendritic Cells. J Histochem Cytochem 58:183-193 (2010) (Abstract)
  • Köhler C, Bista P, Götz J, Schröder H. Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy. Brain Res 1347:111-24 (2010) (Abstract)
  • Mende Y, Jakubik M, Riessland M, Schoenen F, Roßbach K, Kleinridders A, Köhler C, Buch T, Wirth B Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN /Smn splicing. Hum Mol Genet 19:2154-67 (2010) (Abstract)

2009

  • Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning J, Schubert M: Neuronal IGF-1 resistance reduces A(beta)-accumulation and protects against premature death in a model of Alzheimer's disease. FASEB J 23:3315-3324 (2009) (Abstract)
  • Schröder H, Götz J, Pilz K, Kuhlage S, de Vos RAI, Bauer T, Selzer A, Köhler C: Neurofibrillary pathology in the brainstem of the tau mutant pR5 mouse. In: New trends in Alzheimer and Parkinson related disorders: ADPD 2009. A Fisher, I Hanin I (Hrsg.). Medimond 233-237 (2009)

2008

  • Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M: IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination. J Neurochem 107:907-17 (2008) (Abstract)

2007

 

  • Heiss WD, Eggers C, Szelies B, Bauer B, Wienhard K, Schröder H, Herholz K: Imaging of acetylcholine esterase activity in brainstem nuclei involved in regulation of sleep and wakefulness. Eur J Neurol 14:690-693 (2007) (Abstract)
  • Moser N, Mechawar N, Jones I, Gochberg-Sarver A, Orr-Urtreger A, Plomann M, Salas R, Molles B, Marubio L, Roth U, Maskos U, Winzer-Serhan U, Bourgeois J-P, Le Sourd A-M, De Biasi M, Schröder H, Lindstrom J, Maelicke A, Changeux J-P, Wevers A: Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures. J Neurochem 102:479-492 (2007) (Abstract)

2006

 

  • Deuther-Conrad W, Wevers A, Becker G, Schildan A, Patt M, Sabri O, Steinbach J, Brust P: Autoradiography of 2-[18F]F- A-85380 on nicotinic acetylcholine receptors in the porcine brain in vitro. Synapse 59:201-210 (2006) (Abstract)
  • Peeva GP, Angelova SK, Guntinas-Lichius O, Streppel M, Irintchev A, Schütz U, Popratiloff A, Savaskan NE, Bräuer AU, Alvanou A, Nitsch R, Angelov DN: Improved outcome of facial nerve repair in rats is associated with enhanced regenerative response of motoneurons and augmented neocortical plasticit. Eur J Neurosci 24:2152-2162 (2006) (Abstract)

2005

 

  • Köhler C, Ebert U, Baumann K, Schröder H: Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels. Neurobiol Dis. 20:528-540 (2005) (Abstract)
  • Lain E, Penke B, Delacourte A, Gündisch D, Schröder H, Witter B: Effects of Aβ1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the τ-protein and on the α7 nicotinic acetylcholine receptor in vitro. Eur J Neurosci 21:879-888 (2005) (Abstract)

2004

 

  • Herholz K, Weisenbach S, Zündorf G, Lenz O, Schröder H, Bauer B, Kalbe E, Heiss W-D: In-vivo study of acetylcholine esterase in basal forebrain, amygdala, and cortex in mild to moderate Alzheimer disease. Neuroimage 21:136-143 (2004) (Abstract)
  • Korkmaz Y, Baumann MA Schröder H, Behrends S, Addicks A, Bloch W: Localization of the NO-cGMP signal pathway molecules, NOS III-phosphorylation sites, ERK1/2, and Akt/PKB in osteoclasts. J Periodontology 75:1119-25 (2004) (Abstract)
  • Korkmaz Y, Bloch W, Behrends S, Schröder H, Addicks K, Baumann MA: NO-cGMP signaling molecules in the rat epithelial rests of Malassez. Eur J Oral Sci 112:55-60 (2004) (Abstract)
  • Schöndorf T, Ebert MP, Hoffmann J, Becker M, Moser N, Pur S, Göhring UJ, Weißhaar MP: Hypermethylation of the PTEN Gene in ovarian cancer cell lines. Cancer Letters 207:215-220 (2004) (Abstract)
  • Schubert M, Gautam D, Surjo D, Ueki K, Baudler S, Schubert D, Kondo T, Alber J, Galldiks N, Kustermann E, Arndt S, Jacobs AH, Krone W, Kahn CR, Bruning JC: Role for neuronal insulin resistance in neurodegenerative diseases. PNAS 101: 3100-3105 (2004) (Abstract)

2003

 

  • Baumann MA, Korkmaz Y, Bloch W, Schmidt A, Addicks K, Schröder H: Localization of the neuropeptide galanin in nerve fibers and epithelial keratinocytes of the rat molar gingiva. Eur J Oral Sci 111:175-178 (2003) (Abstract)
  • Burghaus L, Schütz U, Krempel U, Lindstrom J, Schröder H: Loss of nicotinic acetylcholine receptor subunits alpha-4 and alpha-7 in the cerebral cortex of Parkinson patients. Parkinsonism Related Disorders 9:243-246 (2003) (Abstract)
  • Krüger GRF, Marshall GR, Junker U, Schröder H, Buja LM, Wang G: Growth factors, cytokines, chemokines and neuropeptides in the modeling of T-cells. In Vivo 16: 365-386 (2002) (Abstract)
  • Schöndorf T, Göhring UJ, Roth G, Middel I, Becker M, Moser N, Valter MM, Hoopmann M. Time to progression is dependent on the expression of the tumour supressor PTEN in ovarian cancer patients. Eur J Clin Invest 33:256-260 (2003) (Abstract)

2002

  • Gu, W, Wevers A, Schröder H, Grzeschik K-H, Derst Ch, Brodtkorb E, de Vos R, Steinlein O: The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily of leucine-rich repeat proteins. FEBS Lett 519:71-76 (2002) (Abstract)
  • Hofmann N, Lachnit N, Streppel M, Witter B, Neiss WF, Guntinas-Lichius O, Angelov DN: Increased expression of ICAM-1, VCAM-1, MCP-1, and MIP-1alpha by spinal perivascular macrophages during experimental allergic encephalomyelitis in rats. BMC Immunol 3:11 (2002) (Abstract)
  • Krüger GRF, Marshall GR, Junker U, Schröder H, Buja LM, Wang G: Growth factors, cytokines, chemokines and neuropeptides in the modeling of T-cells. In Vivo 16: 365-386 (2002) (Abstract)
  • Streppel M, Azzolin N, Dohm S, Guntinas-Lichius O, Haas C, Grothe C, Wevers A, Neiss WF, Angelov DN: Focal application of neutralizing antibodies to soluble neurotrophic factors improves the quality of axonal pathfinding after peripheral nerve lesions. Eur J Neurosci 15:1327-1342 (2002) (Abstract)
  • Jansen Steur ENH & Wevers A: The cholinergic system in Alzheimer's disease. Curr Opin Psychiatry 15:279-284 (2002)

2001

 

  • Arndt SS, Surjo D: Methods for the behavioural phenotyping of mouse mutants. How to keep the overview. Behav Brain Res 125:39-42 (2001) (Abstract)
  • Burghaus L, Schütz U, Simonnet K, Krempel U, Lindstrom J, Schröder H: Nucleus basalis Meynert lesions and the expression of nicotinic acetylcholine receptor proteins in the rat frontal cerebral cortex. Neurosci Lett. 301:111-114 (2001) (Abstract)
  • Guntinas-Lichius O, Angelov DN, Tomov TL, Dramiga J, Neiss WF, Wewetzer K: Transplantation of olfactory ensheathing cells stimulates the collateral sprouting from axotomized adult rat facial motoneurons. Exp Neurol 172:70-80 (2001) (Abstract)
  • Krenz I, Kalkan D, Wevers A, de Vos RAI, Jansen Steur ENH, Lindstrom J, Pilz K, Nowacki S, Schütz U, Moser N, Witter B, Schröder H: Parvalbumin-containing interneurons of the human cerebral cortex express nicotinic acetylcholine receptor proteins. J Chem Neuroanat 21:239-246 (2001) (Abstract)
  • Schröder H, Schütz U, Burghaus L, Lindstrom J, Kuryatov A, Monteggia L, de Vos RAI, van Noort G, Wevers A, Nowacki S, Happich E, Moser N, Arneric SP, Maelicke A: Expression of the alpha-4 isoform of the nicotinic acetylcholine receptor in the fetal human cerebral cortex. Brain Res Dev Brain Res 132:33-45 (2001) (Abstract)
  • Surjo D, Arndt SS: The Mutant Mouse Behaviour network, a medium to present and discuss methods for the behavioural phenotyping. Physiol Behav 73:691-4 (2001) (Abstract)

2000

 

  • Banerjee C, Nyengaard JR, Wevers A, deVos RAI, Jansen-Steur ENH, Lindstrom J, Pilz K, Nowacki S, Bloch W, Schröder H: Cellular expression of alpha-7 nicotinic acetylcholine receptor protein in the temporal cortex in Alzheimer’s and Parkinson’s disease - A stereological approach. Neurobiol Disease 7:666-672 (2000) (Abstract)
  • Burghaus L, Schütz U, Krempel U, de Vos RAI, Jansen Steur ENH, Wevers A, Lindstrom J, Schröder H: Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients. Mol Brain Res 76:385-388 (2000) (Abstract)
  • Haubrich C, Frielingsdorf V, Herzig S, Schröder H, Schwarting R, Sturm V, Voges J: N-type calcium channel blockers - tools for modulation of cerebral functional units? Brain Res 855:225-34 (2000) (Abstract)
  • Modregger J, Ritter B, Witter B, Paulsson M, Plomann M: All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis. J Cell Sci 113 Pt 24:4511-21, (2000) (Abstract)
  • Wevers A, Burghaus L, Moser N, Witter B, Steinlein OK, Schütz U, Achnitz B, Krempel U, Nowacki S, Pilz K, Stoodt J, Lindstrom J, deVos RAI, Jansen Steur ENH, Schröder H: Expression of nicotinic acetylcholine receptors in Alzheimer’s disease: Postmortem investigations and experimental approaches. Behav Brain Res 113:207-15 (2000) (Abstract)
  • Wevers A, Witter B, Moser N, Burghaus L, Banerjee C, Steinlein OK, Schütz U, de Vos RAI, Jansen Steur ENH, Lindstrom J, Schröder H: Classical Alzheimer features and cholinergic dysfunction: towards a unifying hypothesis? Acta Neurol Scand Suppl 176:42-48 (2000) (Abstract)

1999

 

  • Charton JP, Herkert M, Becker CM, Schröder H: Cellular and subcellular localization of the 2B-subunit of the NMDA receptor in the adult rat telencephalon. Brain Res. 816:609-17 (1999) (Abstract)
  • Steinlein OK, Stoodt J, de Vos RAI, Jansen Steur ENH, Wevers A, Schütz U, Schröder H: Mutation Screening of the CHRNA4 and CHRNB2 nicotinic receptor genes in Alzheimer’s disease. NeuroReport 10:2919-2922 (1999) (Abstract)
  • Wevers A, Monteggia L, Nowacki S, Bloch W, Schütz U, Lindstrom J, Pereira EFR, Eisenberg H, Giacobini E, de Vos RAI, Jansen Steur ENH, Maelicke A, Albuquerque EX, Schröder H: Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer’s disease - Histotopographical correlation with amyloid plaques and hyperphosphorylated tau-protein. Eur J Neurosci 11:2551-2565 (1999) (Abstract)
  • Wevers, A Schröder, H: Nicotinic acetylcholine receptors in Alzheimer's disease. J Alzheimers Dis 1:207-219 (1999) (Abstract)

1998

  • Wevers A, Moser N, Schütz U, Steinlein O, Lindstrom J, deVos R, Giacobini E, Maelicke A, Schröder H: Nicotinic receptors in Alzheimer´s disease - from autopsy studies to organotypic culture models. Int J Geriatr Psycho-Pharmacol 1:158-163 (1998)

1997

  • Birtsch C, Wevers A, Traber J, Maelicke A, Bloch W, Schröder H: Expression of alpha-1 and alpha-5 nicotinic cholinoceptor mRNA in the aging rat cerebral cortex. Neurobiol Aging 18:335-342 (1997) (Abstract)

1996

 

  • Hiemke C, Stolp M, Reuss S, Wevers A, Reinhardt S, Maelicke A, Schlegel S, Schröder H: Expression of alpha subunits of nicotinic acetylcholine receptors on human lymphocytes. Neurosci Lett 214:171-174 (1996) (Abstract)
  • Moser N, Wevers A, Lorke DE, Reinhardt S, Maelicke A, Schröder H: alpha-1 subunit mRNA of the nicotinic acetylcholine receptor in the rat olfacotory bulb. Cellular expression in adult, pre- and postnatal stages. Cell Tissue Res 285:17-25 (1996) (Abstract)

1995

  • Albuquerque EX, Pereira EF, Castro NG, Alkondon M, Reinhardt S, Schröder H, Maelicke A: Nicotinic receptor function in the mammalian central nervous system. Ann N Y Acad Sci 757:48-72 (1995) (Abstract)
  • Lobron Ch, Wevers A, Dämgen K, Rontal D, Birtsch Ch, Heinemann S, Reinhardt S, Maelicke A, Schröder H: Cellular distribution in the rat telencephalon of mRNAs encoding for the alpha-3 and alpha-4 subunits of the nicotinic acetylcholine receptor. Mol Brain Res 30:70-76 (1995) (Abstract)
  • Ostermann C-H, Grunwald J, Wevers A, Lorke D, Lobron C, Reinhardt S, Maelicke A, Schröder H: Cellular expression of alpha-4 subunit mRNA of the nicotinic acetylcholine receptor in the developing rat telencephalon. Neurosci Lett 192:1-4 (1995) (Abstract)
  • Schröder H, de Vos RAI, Jansen EH, Birtsch Ch, Wevers A, Lobron Ch, Nowacki S, Schröder R, Maelicke A: Gene expression of the nicotinic acetylcholine receptor alpha-4 subunit in the frontal cortex in Parkinson´s disease. Neurosci Lett 187:173-176 (1995) (Abstract)
  • Wevers A, Schmidt P, Cserpan E, Cserpan I, Maderspach K, Staak M, Schröder H: Cellular distribution of the mRNA for the kappa-opioid receptor in the human neocortex. Neurosci Lett 195:125-128 (1995) (Abstract)
  • Wevers A, Sullivan JP, Giordano T, Birtsch Ch, Monteggia LM, Nowacki S, Arneric S, Schröder H: Cellular distribution of the mRNA for the alpha-7 subunit of the nicotinic acetylcholine receptor in the human cerebral cortex. Drug Dev Res 36:103-110 (1995)

1994

 

  • Klimaschewski L, Reuss S, Spessert R, Lobron C, Wevers A, Heym C, Maelicke A, Schröder H: Expression of nicotinic acetylcholine receptors in rat superior cervical ganglion on mRNA and protein level. Mol Brain Res 27:167-173 (1994) (Abstract)
  • Messamore E, Bogdanovich N, Schröder H, Winblad B: Astrocytes associated with senile plaques possess muscarinic acetylcholine receptors. Neuroreport 5:1473-1476 (1994) (Abstract)
  • Wevers A, Jeske A, Lobron Ch, Birtsch Ch, Heinemann S, Maelicke A, Schröder R, Schröder H: Cellular distribution of nicotinic acetylcholine receptor subunit mRNAs in the human cerebral cortex as revealed by non-isotopic in situ hybridization. Mol Brain Res 25: 122-128 (1994) (Abstract)