2024

Tüscher O., Muthuraman M., Horstmann JP, Horta G., Radyushkin K., Baumgart J., Sigurdsson T., Endle H., Kuhnhäuser P., Götz J., Kepser L-J., … Nitsch R., Vogt, J. (2024) Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders Molecular Psychiatry 2024 May 28. doi: 10.1038/s41380-024-02598-2

2023

Knierim E*, Vogt J*, Kintscher M*, Ponomarenko A, Baumgart J. et al. (2023) Mutations in Plasticity-Related-Gene-1 (PRG-1) protein contribute to hippocampal seizure susceptibility and modify epileptic phenotype Cereb Cortex doi: 10.1093/cercor/bhad051

Gonzales-Escamilla G, Chirumamilla VC, Koirala N, Anwar AR, Tüscher O, Vogt J, Horstmann P, Meyer B, Bonnano GA, Groppa S, Muthuraman M. (2023) Modular segregation drives causality of the dynamic oscillatory network responses during threat processing Brain Communications Feb 17;5(2):fcad035. doi: 10.1093/braincomms/fcad035

Barham M, Andermahr J, Majczynski H, Slawinska U, Vogt J, Neiss WF (2023) Treadmill training of rats after sciatic nerve graft does not alter accuracy of muscle reinnervation. Front Neurol 13:1050822. doi: 10.3389/fneur.2022.1050822

Nawshirwan S, Heucken N, Piekarek N, van Beers T, Fulgham-Scott N, Grandoch A, Neiss WF, Vogt J, Barham M (2023) Morphological, ultrastructural, genetic characteristics and remarkably low prevalence of macroscopic Sarcocystis species isolated from sheep and goats in Kurdistan region, Iraq Front Vet Sci. doi:10.3389/fvets.2023.122579

2022

Endle H, Horta G, Stutz B, Muthuraman M… Horvath TL, Nitsch R & Vogt J (2022). AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids. Nature Metabolism 4(6):683-692

Hanuscheck N, Thalman C, Domingues M, Schmaul S, Muthuraman M, Hetsch F, Ecker M, Endle H … Vogt J*, Vogelaar CF*, Zipp F* (2022) Interleukin-4 receptor signaling modulates neuronal network activity. Journal of Experimental Medicine 219(6):e20211887

Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch I, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J (2022) Inhibition of the enzyme autotaxin rebalances overexcitation in stroke. Science Translational Medicine 14 (641):eabk0135

Barham M, Streppel M, Guntinas-Lichius O, Fulgham-Scott N, Vogt J, Neiss WF (2022) Treatment With Nimodipine or FK506 After Facial Nerve Repair Neither Improves Accuracy of Reinnervation Nor Recovery of Mimetic Function in Rats Front Neurosci 16:895076. Doi: 10.3389/fnins.2022.895076

2021

Ye l, Ji H, TuCH, Kappl M, Koynow K*#, Vogt J*#, Butt HJ* (2021) Carbon Nanotube-hydrogel composites facilitate neuronal differentiation while maintaining homeostasis of network activity. Adv Materials 33(41):e2102981 *senior authors #correspondence authors

Fischer C, Endle H… Vogt J*, Tegeder I* (2021) Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2. Cellular and Molecular Life Sciences 78 (3): 1029 - 1050 *contributed equally as senior author

Iwama T, Kano K, Saigusa D, Ekroos K, van Echtern-Deckert G, Vogt J, Aoki J. (2021) Development of an On-Tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag. Anal Chem. 93(8):3867 – 3875

2018

Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigrudsson T…  Vogt J (2018) Synaptic phospholipids as a new target for cortical hyperexcitability and E/I-balance in psychiatric disorders. Molecular Psychiatry 23:1699-1710

Schneider P, Petzold S, Sommer A, Nitsch R, Schwegler H, Vogt J*, Roskoden T*. (2018) Altered synaptic phospholipid signaling in PRG-1 deficient mice induces exploratory behavior and motor hyperactivity resembling psychiatric disorders. Behav Brain Res 336:1-7 (*equal contributing last authors)

Gonzales-Escamilla G, Chirumamilla VC, Meyer B, Bonertz T, von Grotthus S, Vogt J, et al., (2018) Excitability regulation in the dorsomedial prefrontal crotex during sustained instructed fear responses: a TMS-EEG study. Science Reports 8(1): 14506

Vogelaar CF, Mandal S, Lerch S, Birkner K, Birkenstock J, Bühler U, Schnatz A, Raine CS, Bittner S, Vogt J, Kipnis J, Nitsch R, Zipp F (2018) Fast direct signaling via the IL-4 receptor as therapeutic target in neuroinflammation Science Translational Medicine 10(430)

Ellwardt E, Pramanik G, Luchtmann D, Novkovic T, Jubal ER, Vogt J, Arnoux I, Vogelaar CF, Mandal S, Schmalz M, Barger Z, de Azua IR, Kuhlmann T, Lutz B, Mittmann T, Bittner S, Zipp F, Stroh A (2018) Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nature Neuroscience 21(10):1392-1403

2017

Vogt J, Kirischuk S, Unichenko P, Schlüter L, Pelosi A, Endle H, Yang JW, Schmarowski N, Cheng J, Thalman C,  Strauss U, Prokudin A,  Bharati BS, Aoki J, Chun J, Lutz B, Luhmann HJ, Nitsch R (2017) Synaptic Phospholipid Signaling Modulates Axon Outgrowth via Glutamate-dependent Ca2+-mediated Molecular Pathways. Cerebral Cortex 27(1):131-145

Schmitz K, Brunkhorst R, de Bruin N, Mayer C, Ferreiros N, Häussler A, Schiffmann S, Parnham M, Tunaru S, Chun J, Offermanns S, Förch C, Scholich K, Vogt J, Wicker S, Lötsch J, Geisslinger G, Tegeder I. (2017) Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis. Acta Neuropathologica Communications 5:42 

2016

Cheng J, Sahani S, Hausrat TJ, Yang JW, Endle H, Liu X, Li Y, Böttche R, Radyushkin K, Hoerder-Suabedissen A… Vogt J (2016) Precise somatotopic thalamocortical axon guidance depends on LPA-mediated PRG-2/Radixin signaling. Neuron 92(1):126-142.

Liu X, Huai J, Endle H, Schlüter L, Fan, W, Li Y, Richers S, Yurugi H, Rajalingam K, Ji H… Vogt J (2016) PRG-1 regulates synaptic plasticity via intracellular PP2A/ß1-integrin signaling. Developmental Cell 8;38(3):275-90

Unichenko P, Kirischuk S, Yang JW, Baumgart J, Roskoden T, Schneider P, Sommer A, Nitsch R, Vogt J*, Luhmann HJ* (2016) Plasticity-related gene 1 affects mouse barrel cortex function via strengthening of glutamatergic thalamocortical transmission. Cerebral Cortex 26, 3260-3272 (*equal contributing last authors)

Vogt J, Yang JW, Mobascher A, Cheng J, Li Y, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, et al. (2016). Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. EMBO Mol Med. 8, 25-38

Petzold S, Sommer B, Krober A, Nitsch R, Schwegler H, Vogt J*, and Roskoden T* (2016). NT-3 protein levels are enhanced in the hippocampus of PRG1-deficient mice but remain unchanged in PRG1/LPA2 double mutants. Neuroscience letters. 612:145-8. (*equal contributing last authors)

Rocha PR, Medeiros MC, Kintzel U, Vogt J, Araújo IM, Mestre AL, Mailänder V, Schlett P, Dröge M, Schneider L, Biscarini F, de Leeuw DM, Gomes HL (2016) Extracellular electrical recording of pH-triggered bursts in C6 glioma cell populations. Science Advances  2(12):e1600516.

2015

Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani S, Hechler D, Golz G, Rosenberger K, Kammertons T, Vogt J, Vogelaar C, Siffrin V…. Nitsch R, Zipp F, Kipnis J (2015) MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. The Journal of Clinical Investigation 125: 699-714

Greenman R, Gorelik A, Sapir T, Baumgart J, Zamor V, Segal-Salto M, Levin-Zaidman S, Aidinis V, Aoki J, Nitsch R, Vogt J, Reiner O (2015) Non-cell autonomous and non-catalytic activities of ATX in the developing brain. Frontiers in neuroscience (Neurogenesis) 9: 53

Almeida R, Berzina Z, Arnspang EC, Baumgart J, Vogt J, Nitsch R, Ejsing CS (2015) Quantitative spatial analysis of the mouse brain lipidome by pressurized liquid extraction surface analysis. Analytical Chemistry 87: 1749-1756

Further selected papers

Distler U, Schmeisser MJ, Pelosi A, Reim D, Kuharev J, Weiczner R, Baumgart J, Boeckers TM, Nitsch R, Vogt J*, Tenzer S* (2014) In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Proteomics 14: 2607-2613 (*equal contributing last authors)

Vogt J, Glumm R, Schluter L, Schmitz D, Rost BR, Streu N, Rister B, Suman Bharathi B, Gagiannis D, Hildebrandt H, Weinhold B et al. (2012) Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting. Cellular and molecular life sciences : CMLS 69:1179-1191.

Gaaya A, Poirier O, Mougenot N, Hery T, Atassi F, Marchand A, Saulnier-Blache JS, Amour J, Vogt J, et al., Lompre AM, Soubrier F, Nadaud S (2012) Plasticity-related gene-1 inhibits lysophosphatidic acid-induced vascular smooth muscle cell migration and proliferation and prevents neointima formation. American journal of physiology Cell physiology 303:C1104-1114.

Fietz SA, Lachmann R, Brandl H, Kircher M, Samusik N, Schroder R, Lakshmanaperumal N, Henry I, Vogt J, Riehn A, Distler W, Nitsch R, Enard W, Paabo S, Huttner WB (2012) Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal. PNAS 109:11836-11841.

Magno L, Kretz O, Bert B, Ersozlu S, Vogt J, Fink H, Kimura S, Vogt A, Monyer H, Nitsch R, Naumann T (2011) The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur. J. Neurosci. 34:1767-1782.

Pulvers JN, Bryk J, Fish JL, Wilsch-Brauninger M, Arai Y, Schreier D, Naumann R, Helppi J, Habermann B, Vogt J, Nitsch R, Toth A, Enard W, Paabo S, Huttner WB (2010) Mutations in mouse Aspm cause not only microcephaly but also major defects in the germline. PNAS 107:16595-16600.

Fietz SA, Kelava I, Vogt J, Wilsch-Bräuninger M, Stenzel D, Fish JL, Corbeil D, Riehn A, Distler W, Nitsch R, Huttner WB (2010) Outer subventricular zone progenitors of human and ferret cerebral cortex retain epithelial properties and expand via integrin signaling. Nature Neuroscience 13, 690-699.

Vogt J, Paul F, Aktas O, Muller-Wielsch K, Dorr J, Dorr S, Bharathi BS, Glumm R, Schmitz C, Steinbusch H, Raine CS, Tsokos M, Nitsch R, Zipp F (2009) Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Annals of Neurology 66:310-322.

Trimbuch T*, Beed P*, Vogt J*, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U et al. (2009) Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell 138:1222-1235. 

Brandt N, Franke K, Rasin MR, Baumgart J, Vogt J, Khrulev S, Hassel B, Pohl EE, Sestan N, Nitsch R, Schumacher S (2007) The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. Embo J 26:2371-2386. 

Aktas O, Smorodchenko A, Brocke S, Infante-Duarte C, Schulze Topphoff U, Vogt J, Prozorovski T, Meier S, Osmanova V, Pohl E, Bechmann I, Nitsch R, Zipp F (2005) Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron 46:421-432.

Brinks H*, Conrad S*, Vogt J*, Oldekamp J*, Sierra A*, Deitinghoff L, Bechmann I, Alvarez-Bolado G, Heimrich B, Monnier PP et al.  (2004) The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience 24:3862-3869.